TLR3 anticorps (PE)
Aperçu rapide pour TLR3 anticorps (PE) (ABIN2567450)
Antigène
Voir toutes TLR3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Specificité
- The TLR3.7 monoclonal antibody specifically reacts with human CD283 (TLR3), a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain.
-
Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
-
Isotype
- IgG1 kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.2 mg/mL
-
Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
-
Stock
- 4 °C
-
Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
-
-
- TLR3 (Toll-Like Receptor 3 (TLR3))
-
Autre désignation
- CD283
-
Sujet
- The TLR3.7 monoclonal antibody specifically reacts with human CD283 (TLR3), a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. It is expressed by dendritic cells and recognize double-stranded RNA and polyinosine-polycytidylic acid. Upon ligand binding, CD283 induces type I interferon production and activation of the nuclear factor kappa-light-chain-enhancer of activated B cells complex (NF-κB).
-
ID gène
- 7098
-
UniProt
- O15455
-
Pathways
- Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
Antigène
-